Proplylactic treatment of asthma.
● Chronic treatment of asthma associated with allergy.
● Seasonal and perennial rhinitis.

Montelukast is a Leukotriene receptor antagonists.(is used for maintenance treatment of asthma and to relive symptoms of seasonal allergies) It is a selective and orally active leukotrien antagonist that inhibits the cysteinyl leukotrien CysLT1 receptor.
Levocetirizine is a third — generation non — sedative antihistamine.(is prevents the release of other allergy chemicals and increased blood supply to the area, and provides relief from the typical symptoms of hay fever). Levocetirizine, the R — entaiomer of Cetirizine, is a potent and selective antagonist of peripheral H1 — receptors.
It has been demonstrated by recent studies concomitant administration of an antileukotrien (montelukast) and an antihistamine (levocetirizine), shows significantly better symptoms relief compared with the modest improvement of rhinitis symptomatology with each of the treatments alone.
Montelukast:Add — on therapy for the treatment of patients, 6 years old or older, with mild to moderate asthma in adequately controlled on 'as required' short — acting β — agonist and inhaled corticosteroids. Monteluakst may offer an alternative to Theophylline as add — on therapy is asthma poorly controlled by short acting β — agonist and inhaled corticosteroids.
Levocetirizine: skin allergy like food and drug allergy or atopic dermatitis, chronic idiopathic urticaria.