FELA-6

COMPOSITION: DEFLAZACORT 6 MG

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Anti-inflammatory, Immunosuppressant

Deflazacort is a glucocorticoid used as an anti-inflammatory and immunosuppressant.

Pharmacokinetics

Deflazacort, derived from prednisolone, is a corticosteroid with mainly glucocorticoid activity. An anti-inflammatory dose of 6 mg deflazacort is equiv to 5 mg prednisolone.

Deflazacort Adverse Reactions / Deflazacort Side Effects

GI disturbances, musculoskeletal, endocrine, neuropsychiatric, ophthalmic, fluid and electrolyte disturbances; susceptible to infection, impaired healing, hypersensitivity, skin atrophy, striae, telangiectasia, acne, myocardial rupture following recent MI, thromboembolism.

Special Precautions

Adrenal suppression and infection, child, adolescents, elderly, history of TB and steroid myopathy, hypertension, recent MI, CHF, liver failure, renal impairment, DM and glaucoma (including family history), osteoporosis, corneal perforation, severe affective disorders, epilepsy, peptic ulcer, hypothyroidism, pregnancy and lactation.

Other Drug Interactions

Antacids, ACE inhibitors, acetazolamide, adrenergic neuron blockers, antidiabetics, aspirin, barbiturate, β-blockers, calcium-channel blockers, carbamazepine, carbenoxolone, cardiac glycosides, clonidine, coumarins, diazoxide, diuretics, erythromycin, hydralazine, ketoconazole, methotrexate, methyldopa, mifepristone, minoxidil, moxonidine, nitrates, nitroprusside, NSAIDs, oestrogens, phenytoin, primidone, rifamycins, ritonavir, somatropin, β2 sympathomimetics, theophylline, vaccines.

Other Interactions

Food Interaction: Salad and vegetable diet including alcohol may affect anticoagulant control.

List of Contraindications

Deflazacort and Pregnancy

Caution when used during pregnancy

Deflazacort and Lactation

Caution when used during lactation

Deflazacort and Other Contraindications

Systemic infection; live virus vaccines in those receiving immunosuppressive doses.

 

 

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